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Intrauterine insemination (IUI) is one of the procedures of ART, during which specially treated sperm (husband or donor) enters the uterus of a woman through a thin plastic catheter introduced into the cervical canal during ovulation. Sperm processing is performed to increase the concentration of active sperm and to remove immobile, semen, leukocytes. As a result, semen volume is reduced and fertility is significantly increased.

The procedure of intrauterine insemination can be performed both in the natural menstrual cycle and stimulated depending on the specific situation. Ovulation stimulator is prescribed by the doctor after ultrasound. One or two IUI procedures may be performed in one cycle.

Indications for conducting the IUI:

For men:

  • reduced spermogram index
  • use of cryopreserved semen
  • sexual disorders 
  • high level of antisperm antibodies

For women:

  • ovulation disorders
  • antisperm antibodies
  • cervical factor
  • idiopathic infertility


  • absence or obstruction of the fallopian tubes
  • developmental abnormalities, extragenital diseases in which pregnancy is impossible
  • tumors
  • acute inflammatory processes of any localization
  • genital tract infections


The effectiveness of the procedure depends on many factors, the main ones being the age of the woman, the duration of infertility, and the sperm index. As the effectiveness of the IUI procedure does not exceed 20%, artificial insemination programs should be used for couples who have not been pregnant for 3-4 cycles.

Donor insemination is a procedure for using cryopreserved donor sperm to an unmarried woman or couple where the man is infertile or is a carrier of hereditary diseases.